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花生四烯酸是細(xì)胞膜的主要組分之一, 通過環(huán)氧合酶(cyclooxygenase, COX)和 脂 氧 合 酶 (lipoxygenase, LOX)途 徑分別產(chǎn)生以前列腺素E2(prostaglandin E2, PGE2)和白三烯B4(leukotriene B4, LTB4)為代表的類花生酸類物質(zhì)。LTB4由響應(yīng)炎癥介質(zhì)的白細(xì)胞產(chǎn)生, 并活化多種白細(xì)胞功能, 包括白細(xì)胞聚集、離子流活化、增強(qiáng)溶酶體中酶的釋放、超氧陰離子的產(chǎn)生、趨化等。白細(xì)胞活化后,血漿中LTB4的水平從<100pg>100ng/ml。LTB4在白細(xì)胞和肝細(xì)胞中代謝為20-羥基LTB4和20-羧基LTB4, 不排泄在尿液。
產(chǎn)品列表
品牌 | 產(chǎn)品名稱 | 產(chǎn)品貨號 | 規(guī)格 |
Cayman | Leukotriene B4 ELISA Kit | 520111-480 solid wells | 480 solid wells |
Cayman | Leukotriene B4 ELISA Kit | 520111-480 strip wells | 480 strip wells |
Cayman | Leukotriene B4 ELISA Kit | 520111-96 solid wells | 96 solid wells |
Cayman | Leukotriene B4 ELISA Kit | 520111-96 strip wells | 96 strip wells |
Cayman | Leukotriene B4 Express ELISA Kit | 10009292-480 solid wells | 480 solid wells |
Cayman | Leukotriene B4 Express ELISA Kit | 10009292-480 strip wells | 480 strip wells |
Cayman | Leukotriene B4 Express ELISA Kit | 10009292-96 solid wells | 96 solid wells |
Cayman | Leukotriene B4 Express ELISA Kit | 10009292-96 strip wells | 96 strip wells |
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