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多不飽和脂肪酸(PUFAs)是重要的營養(yǎng)物質(zhì),當飲食中不存在足夠的量時,會表現(xiàn)出明顯的缺乏綜合征。實際上所有細胞中的花生四烯酸都被酯化成膜磷脂,其存在通過多個相互連接的途徑受到嚴格的調(diào)節(jié)。游離花生四烯酸是類花生酸第二信使生物合成的瞬時關(guān)鍵底物。受體刺激的游離花生四烯酸的釋放、代謝和再攝取都是細胞信號和炎癥的重要方面。
嘌呤霉素是一種氨基核苷抗生素,來源于S. alboniger,通過導(dǎo)致新生多肽鏈過早終止來阻斷原核生物和真核生物中的蛋白質(zhì)合成。嘌呤霉素分子的一部分類似于氨酰化tRNA的3’末端。它進入核糖體的A位點,并在肽基轉(zhuǎn)移酶中心附著于生長中的多肽鏈。導(dǎo)致嘌呤酰化新生鏈的形成和過早的鏈釋放。3’位置含有一個酰胺鍵,而不是tRNA的正常酯鍵,使其更能抵抗水解并停止核糖體的活性。
Antipain . dihydrochloride抑制劑由Adipogen公司生產(chǎn),該產(chǎn)品貨號為AG-CP3-7002-M025,規(guī)格是25 mg。如需購買該產(chǎn)品,請聯(lián)系代理商欣博盛生物。
Ganglioside GD1b . disodium salt (bovine brain)化合物由Adipogen公司所生產(chǎn),該款產(chǎn)品貨號是AG-CN2-9004-M001,規(guī)格為1 mg。如需購買該產(chǎn)品,請聯(lián)系我們欣博盛生物。
CleanTag® Small RNA Library Prep Kit is compatible with Illumina® and Ion Torrent™ technology and contains all necessary components for small RNA library preparation for next-generation sequencing. T…
Ganglioside GQ1b . tetrasodium salt (bovine brain) Specifically promotes neural differentiation of human neuroblastoma cells.
Y-27632 is a highly potent, cell permeable, selective and ATP competitive inhibitor of ROCK1 and ROCK2 (IC50=800nM). It acts as a potent inhibitor of agonist-induced Ca2+sensitization of myosin ……
Sphingosine-1-phosphate (1-SPP) is a putative second messenger that mobilizes calcium from intracellular stores via an IP3 independent pathway, activation of phospholipase D and stimulation of ……
JC-1 is a very sensitive fluorescent probe to test Pgp activity. In acute myeloid leukemia (AML) samples JC-1 is capable of distinguishing between resistant, intermediate and sensitive groups……