The CI:A3-1 monoclonal antibody reacts with mouse F4/80 also known as EMR1. F4/80 is a 160 kDa membrane glycoprotein belonging to the EGF-TM7 family. F4/80 is expressed on most tissue macrophages including peritoneal, lung, gut, thymus and splenic red pulp macrophages, as well as Kuffer cells, Langerhans cells, bone marrow stromal cells, and a subset of dendritic cells. F4/80's cognate ligand has not been identified however studies in mice have shown that F4/80 is important for cytokine production and induction regulatory T cells.

產(chǎn)品名稱(chēng):InVivoMab anti-mouse F4/80

反應(yīng)種屬:mouse

宿主來(lái)源:rat

實(shí)驗(yàn)應(yīng)用:in vivo Monocyte/Macrophage depletion, Functional assays, Immunohistochemistry (paraffin), Immunohistochemistry (frozen), Flow cytometry

同種型:IgG2b

免疫原:C57BL/6 mouse thioglycollate stimulated peritoneal macrophages

克隆性:Monoclonal

克隆號(hào):CI:A3-1

產(chǎn)品濃度:Lot specific,typically between 4-11 mg/ml

保存溫度:Undiluted at 4°C in the dark

運(yùn)輸溫度:Ship with adequate amount of blue ice to ensure the product remains at 4°C for the duration of transit

預(yù)期分子量:150 kDa

產(chǎn)品形式:液體

有效期:One year from the date of receipt if stored as recommended

產(chǎn)地:美國(guó)

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