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更新時(shí)間:2022-03-03
5-formyl-dC is mutagenic and has been shown to induce the 5-fC →T transition mutation as well as 5-fC →A and 5-fC →G transversion mutations during DNA synthesis, particularly in methylated CpG region…
Description
5-formyl-dC is mutagenic and has been shown to induce the 5-fC →T transition mutation as well as 5-fC →A and 5-fC →G transversion mutations during DNA synthesis, particularly in methylated CpG regions (Kamiya et al., Münzel et al.)
Product Details
Catalog NoN-2064
Purity≥90% by AX-HPLC
Extinction Coefficient11,000 Lmol-1cm-1 at 283 nm
Molecular FormulaC10H16N3O14P3 (free acid)
Molecular Weight495.10 g/mole (free acid)
Salt FormLi+
Concentration100 mM
BufferH2O
Recommended Storage-20°C or below
Other Name(s)5-Formyl-dCTP, 5-fdCTP,5-CHO-dCTP, 5-Fo-dCTP
ApplicationAptamers, Epigenetics/DNA Damage, In vitro Transcription, Mutagenesis, Photocrosslinking Studies
Backbone5'-Triphosphate
Base Analog(s)Cytidine
Sugar Type(s)DNA
Nucleotide CategoryBase Modified DNA